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MORGANTOWN, W.Va. -- Skyler Howard played through a rib injury and Rushel Shell missed most of the second half with leg cramps, yet West Virginia overcame setbacks to their top two offensive threats to break a five-game losing streak to Southeastern Conference teams.Backup running back Justin Crawford rushed for 101 yards and a touchdown filling in for Shell, and Howard stayed in the game to lead the Mountaineers to a 26-11 win over Missouri on Saturday.Well take it, said West Virginia coach Dana Holgorsen. Weve got a lot of work to do.So does Missouri, which lost in the debut for coach Barry Odom and fell in an opener for the first time since 2001, which was the first season under previous coach Gary Pinkel.Howard was hurt when he was tackled by Missouris Donavin Newsom while sliding during a run near halftime. Trainers worked on his ribs before the second-half kickoff and he returned to the game.Holgorsen said Howard is sore but no ribs were broken.He knew we needed him, Holgorsen said. The kid is a competitor and is going to do anything ... to help the team win.Howard didnt attempt a carry the rest of the game. He finished 23 of 35 for 235 yards with no touchdowns and an interception.In the brief time Howard sat out, backup quarterback William Crest lost a fumble and Chris Chugunov threw an interception.When guys go down, (other) guys need to go in and play at a high level, Holgorsen said. Some did. Some didnt.Crawford did. The junior college transfer got most of the carries after Shell walked off the field gingerly early in the third quarter and didnt return. Holgorsen said Shell had leg cramps and hes fine.Crawford had a 1-yard scoring run in the third quarter.From a teammate perspective, its good to know when you come off the field theyre putting someone in that is just as good as you, Shell said.Shell finished with 90 yards, including a 23-yard TD in the first quarter. He said he didnt want to return to the game after leaving and mess up the flow and the tempo of the offense.Missouri struggled most of the game under sophomore quarterback Drew Lock, who threw an 8-yard scoring pass to Chris Black with under two minutes left.I dont feel like I did a very good job on this, Odom said. Im obviously very thankful and honored to be the head coach. But Ive got a job to do and I didnt get it done today.THE TAKEAWAYMISSOURI: New offensive coordinator Josh Heupel has two weeks to get the Tigers ready for the grueling Southeastern Conference schedule. The Tigers were lethargic against a West Virginia defense that had nine new starters. Lock finished 23 of 51 for 280 yards.Odom said there was some good and some bad about Locks performance.Hes going to continue to get better, Odom said.WEST VIRGINIA: Like many games last season, the Mountaineers had trouble reaching the end zone following long drives. Four stalled inside the Missouri 10, all leading to short field goals by Mike Molina.Thats not good, Holgorsen said. Theres going to be times where those field goals need to be touchdowns. We have to do a better job of finishing drives.UP NEXTMISSOURI: Tigers fans get to see how Odom does for themselves in the home opener against Eastern Michigan -- a 61-14 winner over Mississippi Valley State -- before Missouris SEC home opener with Georgia a week later.WEST VIRGINIA: The Mountaineers welcome ex-Nebraska coach Bo Pelini in their first-ever meeting with Youngstown State, which gave Pittsburgh a scare on the road a year ago. Lorenzen Wright Jersey . 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SPREAD -- Lions 3-4-1, Vikings 5-2SERIES RECORD -- Vikings lead 71-36-2LAST MEETING -- Vikings beat Lions 28-19, Oct. 25, 2015LAST WEEK -- Lions lost to Texans 20-13; Vikings lost to Bears 20-10AP PRO32 RANKING -- Lions No. 17, Vikings No. 8LIONS OFFENSE -- OVERALL (21), RUSH (27), PASS (16).LIONS DEFENSE -- OVERALL (23), RUSH (17), PASS (19).VIKINGS OFFENSE -- OVERALL (31), RUSH (31), PASS (28).VIKINGS DEFENSE -- OVERALL (2), RUSH (8) PASS (4).STREAKS, STATS AND NOTES -- Vikings have won 16 of last 18 at home vs. Lions, losing only in 2011 and 2014. ... Lions have lost all four games by seven points or fewer and total of 18 points. ... Lions QB Matthew Stafford has thrown five interceptions in 12 career games vs. Vikings but been sacked 39 times for total of 274 yards lost. ... Stafford has nine TD passes without interception and cumulative 115.0 passer rating over last four games. ... Lions DE Ezekiel Ansah has 4+ sacks and two forced fumbles in last four games vs. Vikings. ... Lions bacckup RB Zach Zenner is native of Eagan, Minnesota, about 15 miles southeast of U.ddddddddddddS. Bank Stadium. ... Pat Shurmur takes over as offensive coordinator for Vikings after resignation of Norv Turner. Offense has not turned over ball in three home games. ... Vikings have allowed 104 points, fewest at seven-game mark for franchise since 1977, when they gave up 91. ... Vikings have fourth-worst sacks-per-pass-play rate in league, taking 11 sacks over last two games while scoring only 10 points in each. ... Vikings WR Stefon Diggs scored first career TD vs. Lions last year. ... Vikings DE Everson Griffen has 7+ sacks in past seven games against Lions. ... Fantasy Tip: Lions RB Theo Riddick had season-high 19 touches and 133 total yards vs. Texans. Diggs was targeted career-high 13 times last week, totaling 76 yards and score on eight receptions.---AP NFL website: http://www.pro32.ap.org and AP NFL coverage on Twitter: http://www.twitter.com/AP-NFL ' ' '