BARCELONA, Spain -- Lionel Messi netted two goals within 15 minutes of coming on as a substitute to give Barcelona a 4-2 comeback win over Real Betis on Sunday and push his team to the brink of the Spanish league title. After his teammates had rallied back twice to level at 2-2, Messi went on in the 56th and four minutes later curled in a free kick to extend his record scoring streak to 21 straight league appearances. The Argentina forward struck again in the 71st by polishing off a superb passing combination with Andres Iniesta and fellow goalscorer Alexis Sanchez to reach the 60-goal mark in all competitions for the second straight season. "We know Messi is the best," Barcelona defender Gerard Pique said. "We know every time he comes on he will give us something." Barcelona leads by 11 points with four rounds to go and would clinch its 22nd domestic crown if defending champion Real Madrid drops points against Malaga on Wednesday. Messi has been hampered for the past month by a right hamstring injury. Since hurting his leg on April 2, the four-time world player of the year has missed four games-- including Wednesdays stinging 3-0 loss to Bayern Munich that sealed its exit from the Champions League-- and come off the bench in two more before Sundays match. Like last weeks game at Athletic Bilbao, Messi looked fit enough as he again tilted the match in Barcelonas favour. "Against Messi, you cant do anything," said Betis coach Pepe Mel, whose team remained in seventh place. "At San Mames he ran through opposing players like they were cones. And here, the first ball he touches he puts it right inside the corner of the goalframe. It was like it had been scripted. It was suddenly a big party and went down from there." Messis double gave took his league-leading goal tally to 46 for the season, and kept him on pace to beat his own record of 50 from the last campaign. Elsewhere on Sunday, Real Zaragoza beat Rayo Vallecano 3-0 to escape the relegation zone, while Mallorca remained in last place after drawing 1-1 with Levante. Sevilla, meanwhile, rolled to a 3-0 victory over Espanyol to move into eighth place and stay in the hunt for a Europa League berth. Barcelona showed signs of still feeling the effects of its midweek defeat to Bayern that completed its 7-0 dismantling of the Catalan side over their two-leg semifinal. Barcelona was sluggish at the start and in the second minute its defence was slow to react to an apparently routine high ball that bounced through to Dorlan Pabon, who expertly slotted it beyond goalkeeper Jose Pinto, playing for the injured Victor Valdes. Whistles of frustration were immediately heard from the demanding Camp Nou crowd, and they combined with the drizzling rain to further damper the hosts spirits just when they should have been trying to take a step toward the league title. Barcelona was quick to react, and with Messi on the bench, it fell to playmaker Iniesta to unlock Betis defence in the ninth when he picked out Alexis at the far post to nod in his cross. Barcelona pressed for a second goal with David Villa squandering two good chances before Cristian Tello hit the crossbar. But it was Betis that went ahead again-- this time against the run of play-- with Ruben Perezs unstoppable long strike from well outside the area that Pinto had no chance to keep out two minutes before halftime. "Football was a little cruel with us in the first half," Pique said. "We created a lot of scoring opportunities while they scored on the two chances they had, but then it was kind to us in the second half. "We are close to the title. The sooner it comes, the better." Messi started to warm up at the start of the second half to the relief of the home fans who cheered his presence on the sideline. Seconds before coming off for Messi, Villa made up for his earlier misses by knocking Dani Alves cross under goalie Adrian San Miguel with a header after Betis defence has left him unmarked in the box. Messi then took over in his 20th multi-goal game of the season. He had touched the ball just once when he scored an exquisite free kick, bending a left-footed shot just inside the near corner of the goalframe that San Miguel did well to touch but couldnt turn away. Messi almost hit with another free kick in the 69th, with the ball landing on the corner of the goalframe. But his second goal soon came when Messi linked up with Iniesta, who flicked on a no-look pass to play Alexis free in the area. The Chile forward then unselfishly crossed for Messi to tap in and complete the kind of beautiful move that Barcelona is known for and few other teams are capable of performing. Kevin Greene Womens Jersey . The Oilers come in having lost five in a row (0-4-1) and 16 of their last 20 games, dropping a 2-1 decision to the Vancouver Canucks on Tuesday. Heath Miller Womens Jersey .com) - Following a late-game loss to the reigning NBA champs, the Toronto Raptors will look to sustain their recent high-level play as they travel to Indiana to take on the Pacers. http://www.steelersrookiestore.com/Steelers-Joe-Greene-Jersey/ . You can watch the game live on TSN at 7:30pm et/4:30pm pt. The Flyers had won seven of eight before dropping their last two outings on consecutive days over the weekend. Philadelphia was handed a 6-3 loss by the visiting Tampa Bay Lightning on Saturday afternoon before dropping a 4-1 decision to the Rangers the following night in New York City. Ernie Stautner Youth Jersey . After the whistle, Thornton skated the length of the ice, pulled Orpik to the ice from behind and punched him in the face several times. Joe Greene Jersey . Datsyuk will miss Tuesdays game against New Jersey and could be sidelined longer, while Cleary will likely miss at least the next three games. Its been an injury-plagued season for Datsyuk, who has suited up for just 39 games. TOKYO -- Cuban infielder Alex Guerrero has signed a one-year deal with the Chunichi Dragons of Japans Central league.The deal is worth $1.3 million plus incentives, the Central League club announced on its website.The 30-year-old, who can also play outfield, played in 117 major league games for the Los Angeles Dodgers over the 2014 and `15 seaasons batting .dddddddddddd.224 with 11 home runs.He missed most of the 2016 season with a knee injury and was released during the summer.Guerrero was used primarily in left field and at third base with the Dodgers. ' ' '