Saturday, kick-off 14:30TwickenhamEddie Jones England look set to end a 10-year run without a win against South Africa when an under-performing Springboks side take to the field at Twickenham on Saturday.?As they look to continue their 100 percent record under Jones, there has not been a better time to face the Boks, whose most recent performance saw them struggle to draw against the Barbarians last week.In stark contrast, England bossed Australia in their 3-0 series win in the summer and despite a few injuries, their players come into the November international window on the back of some very good club form.?A disappointing Rugby Championship for?Allister Coetzees side culminated in a 57-15 defeat at home to the All Blacks. It is difficult to find a time where expectation was lower among their fans and there is little to show that they will turn things around against England, and push their unbeaten run against them to 13 games.Team newsCourtney Lawes is set to win his 50th cap in a pack that has seen its back-row options limited with James Haskell, Maro Itoje, Jack Clifford, Sam Jones and Mike Williams all missing out through injury. The raft of injuries has given Tom Wood his first opportunity to start for England since the World Cup.?Wasps Elliot Daly got the nod at centre in place of Jonathan Joseph, while Jones will hope the George Ford/Owen Farrell, 10/12 axis, will continue to blossom. On the bench the prospect of Ben Teo will excite English fans, with the centre bringing physicality and neat footwork to the back-line. If he, Kyle Sinckler or Nathan Hughes make an appearance, it will be their first run-out in an England shirt.Springboks head coach Allister Coetzee opted to leave out Bryan Habana from the matchday squad, although the Toulon winger looked to have shaken off a knee injury. He has gone for brute force in his pack, with Lood de Jager, Willem Alberts and Pieter-Steph du Toit providing both physicality and size. They were all replacements in Octobers defeat to the All Blacks and much is expected from all three to enforce their game on England.Damian de Allende and Pat Lambie are the sole survivors from the team that started the defeat to New Zealand in the back-line, but Lambie switches from fullback to fly-half for Saturdays clash.England: Brown, Yarde, Daly, Farrell, May, Ford, Youngs; M. Vunipola, Hartley (captain), Cole, Launchbury, Lawes, Robshaw, Wood, B. VunipolaReplacements:?George, Marler, Sinckler, Attwood, Hughes, Care, Teo, JosephSouth Africa:?Le Roux, Combrinck, Venter, de Allende, Pietersen, Lambie, Paige; Mtawarira, Strauss, Koch, Etzebeth, de Jager, Alberts, du Toit, WhiteleyReplacements:?Mbonambi, Kitshoff, Adriaanse, Mostert, Carr, de Klerk, Goosen, Mapoe.Key head-to-headWhat difference can three players make? That is the big question as South Africa look to avoid a similar thumping to that which was inflicted upon them a month ago. Their pack is not the once feared and all-dominating pack of old. In contrast England come into the game having destroyed Australia up front in the summer and in Mako Vunipola have arguably the best prop in world rugby. He has been in terrifying form for Saracens and if he and brother Billy can have the same influence on Saturday, that they have had at club level, it will decide the outcome. ?Key stats*Englands only decent result against South Africa in 10 years came in the 2012 12-12 draw in South Africa.*Eddie Jones has a 100 percent record since taking charge of England, who are on a 10-game winning streak.*England have won just 12 of the 37 games between the sides, with two draws.WeatherBoth sets of fans will hope the rain forecast will avoid Twickenham for a few hours on Saturday. If it doesnt it could be a very attritional and punishing game for both forward packs.?PredictionEngland will put an end to their abysmal record against the Boks. Eddie Jones side showed in the summer that even when series victory is ensured, there is no let up in their intent. That could spell disaster for South Africa who are still no clearer in knowing which way they should play under?Allister Coetzee. A rack of tries from the explosive England back-line should serve up a comfortable victory by 15 points.? Jared Spurgeon Wild Jersey . "No difference at all," chirped U.S. roommate and linemate James van Riemsdyk. "Its still the same cranky Phil. Jason Zucker Jersey . -- Jacksonville wide receiver Cecil Shorts will likely be a game-time decision whether hell play Sunday in the Jaguars home game against the San Diego Chargers. http://www.authenticwildpro.com/Ryan-suter-wild-jersey/ . Pirlo limped out of Sundays 1-0 win over Udinese after just 13 minutes. Juventus says Pirlo underwent tests on Monday which revealed he has "a second-degree lesion to the collateral medial ligament in his right knee. Mikko Koivu Wild Jersey .H. -- Matt Kenseth made it 2 for 2 in the Chase, holding off teammate Kyle Busch to win Sunday at New Hampshire Motor Speedway. Alex Stalock Wild Jersey . Aaron Harrison scored a 22 points for Kentucky (6-1), which has won four in a row following a Nov. 12 loss to current No. 1 Michigan State. Julius Randle overcame a scoreless first half and added his sixth double-double in as many games with 14 points and 10 rebounds. ENGLEWOOD, Colo. -- C.J. Anderson might be going from breakout to heartbreak.The Denver Broncos were bracing for bad news on their starting running back, who they sent for a second opinion on his ailing right knee Wednesday.Anderson hurt it on an 11-yard run on the final play of the first quarter Monday night against Houston but returned to the game and ran 14 more times for 84 yards to spark Denvers 27-9 win.His 107-yard performance on 16 carries marked his first career 100-yard game before Halloween. Combined with rookie Devontae Bookers big night, the Broncos (5-2) finally snapped out of an offensive funk by rushing for nearly 190 yards.They left the stadium feeling really good about their new 1-2 punch in the backfield, but Anderson showed up sore Tuesday. Theyll know Thursday how much time hell miss.Were just really trying to evaluate it more than anything, coach Gary Kubiak said. He played with it. He did it early in the game. He played through it, he played really well. Actually, he was our offensive MVP. He came in really sore the day after. So, were trying to evaluate where hes at right now.With Anderson down, the Broncos would start Booker on Sunday against San Diego and Kapri Bibbs would back him up.Its kind of up to Book, how much can he handle, what kind of load can he handle? But I think he played really well the other night, Kubiak said. Kapris been chomping. So, well see where C.J.s at.Andersons injury could thwart the momentum they found in their ground game, which opened up passing lanes for their wide receivers by games end as Houston was forced to bring a safety closer to the line of scrimmage to help against the run.Booker, who ran for 83 yards and his first career TD on 17 carries against the Texans, said hes ready for a bigger role if Andersons sidelined.QQuarterback Trevor Siemian said hes comfortable with Booker, too.dddddddddddd.Book is a stud and hes been running really well for us the last couple of weeks, Siemian said. Hopefully we get C.J. back again because you would like to have two that are playing really well. But I have a lot of confidence in Book, Kapri and whoever else is back there.Also Wednesday, tight end A.J. Derby, acquired from New England for a 2017 fifth-round draft pick, practiced with his new teammates for the first time.We think he has a chance to help us really quickly, Kubiak said.Kubiak acknowledged a fifth-rounder was a steep price to pay for a backup this deep into a season, but said injuries to Virgil Green and Jeff Heuerman have stymied the Broncos and we think this kids got a bright future. He added, Id be very comfortable playing him Sunday against the Chargers.Playing behind Rob Gronkowski and Martellus Bennett, Derby played just 36 snaps. But his preseason production -- 15 receptions for 189 yards and a TD -- is roughly what the Broncos tight ends have managed this season.Obviously they have a good room back in New England. It was fun to learn from them, Derby said. ... We have a good room here, as well. Im just excited to compete with those guys.Game notes C Matt Paradis (hip), MLB Brandon Marshall (left hamstring) and NT Sylvester Williams (ankle) also missed practice as did backup C James Ferentz (non-injury). ... Marshall said he hasnt had a pulled hamstring this bad since 2008.---AP NFL website: www.pro32.ap.org and AP NFL Twitter feed: www.twitter.com/AP-NFL---Follow AP Pro Football Writer Arnie Melendrez Stapleton on Twitter: http://twitter.com/arniestapleton ' ' '